Welcome to the webpage of the working group "Experimental Tumorpathology", Institute of Pathology, Universitätsklinikum Erlangen, Friedrich Alexander-University Erlangen-Nuremberg.
On March 1, 2009, Dr. Regine Schneider-Stock, PhD, joined the Institute of Pathology at the University of Erlangen as a W2 Professor of Experimental Tumor Pathology. Our group has been cre-ated to reinforce further the focus of tumor biology at the University hospital. Dr. Regine Schnei-der-Stock, PhD, has a long-standing interest in understanding the molecular pathways of DNA- and cell damage caused by oxidative stress. We have an excellent expertise in molecular-genetic, epigenetic and biochemical analysis of apoptosis induction, and apoptosis resistance mechanisms in gastrointestinal tumors. Main focus is studying the role of Death-associated protein kinase (DAPK1) in colorectal carcinogenesis.
In addition, our group carries out the molecular diagnostics of gastrointestinal stromal tumors (GIST) and malignant mucosal melanomas. The mutation analyses for the c-kit and the PDGFR gene are an impressive example demonstrating how molecular pathology has improved the predic-tion of prognosis and the therapy recommendation for GIST patients.